2015.12.18 Dev Chat

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On Published Lab Results: NG Switch & Cooperativity Puzzle, Successful Player Designs!!!, Johan's Lab Data Spreadsheet, Better In Game Data Browsing, How To Make Hypotheses, Switches Strategy Market & Hashtags, NUPACK, & Eternacon 2016


rhiju: hi everyone [12:04 AM]

Astromon: what is this Sequence peak detcter [12:04 AM]

Jennifer Pearl: i am going to go afline for a moment to move to a better area if no one is online when I get back i will start something [12:04 AM]

Astromon: hi riju [12:05 AM]

Elves: hello! [12:05 AM]

Astromon: hi Elves [12:05 AM]

Astromon: !! [12:05 AM]

Tigerlrg245: oh Hello Elvis :) like your songs! [12:05 AM]

RedSpah: > Elvis [12:05 AM]

Jennifer Pearl: hi rhiju did not see you there [12:05 AM]

Tigerlrg245: hehe i was waiting a week to use that pun [12:05 AM]

Jennifer Pearl: hi Elves [12:05 AM]

RedSpah: hi Elves tho [12:05 AM]

Elves: hi Astro! Jen, Rhiju, tiger :D Red!!! [12:05 AM]

Astromon: sing blue christmas ! [12:06 AM]

Tigerlrg245: @RedSpah what'd that do? [12:06 AM]

Jennifer Pearl: afk for a moment [12:06 AM]

Astromon: the nanorna walkers now have wheels! [12:06 AM]

RedSpah: @Tiger read discription in upper left [12:06 AM]

Elves: i'll have a bluuuuuuuuue christmas, w/o u [12:06 AM]

Astromon: haha nice!!! [12:07 AM]

Astromon: I have a suggestion and a question for when things get slow<< [12:08 AM]

Astromon: haha elves [12:08 AM]

Astromon: im glad this chat was early me and my neph going to see Starwars [12:09 AM]

Elves: nice! have fun astro [12:09 AM]

Tigerlrg245: @Astromon enjoy it, not a fan personally but i heard from someone it's pretty good [12:09 AM]

Astromon: cooL [12:09 AM]

Tigerlrg245: wait so writing www just autolinks a puzzle or did you personally link that? [12:09 AM]

Astromon: some of my very best childhood memories are goping to see Starwars [12:10 AM]

rhiju: hey everyone we have some good news on labs -- johana can tell you about recent results [12:11 AM]

Astromon: Okay! [12:11 AM]

rhiju: he's still getting into chat [12:11 AM]

Tigerlrg245: Is it on one of the new labs or just labs in general? [12:12 AM]

johana: Yes, the NG switches and cooperativity puzzle results have already published [12:12 AM]

Astromon: what? [12:12 AM]

Astromon: wow! [12:12 AM]

johana: The logic switches also showed some great results and will hopefully be posted soon. [12:12 AM]

Astromon: i was able to get 5 er 6 ms2 into the coop lab [12:12 AM]

Elves: woohoo! [12:12 AM]

Astromon: on one design<< [12:12 AM]

johana: As a Christmas gift, perhaps :-) [12:12 AM]

Elves: *high five* [12:13 AM]

Tigerlrg245: wait, all of the NGs from last week's lab? [12:13 AM]

johana: The first RNA in/out puzzles are also on their way [12:13 AM]

Tigerlrg245: @astromon i tried that too, only got four though i think [12:13 AM]

johana: The data are mostly quantified but need more analysis [12:13 AM]

Astromon: are we talking about the labs just just went up? [12:13 AM]

Tigerlrg245: ^ ? [12:13 AM]

rhiju: the data are actually for labs from earlier in the year.  [12:14 AM]

Astromon: which labs?!!! [12:14 AM]

jnicol: NG http://www.eternagame.org/web/lab/6089624/ [12:14 AM]

johana: @Tiger: No,  the NG from Round 98. They led us to post the recent labs which will test some specific hypotheses [12:14 AM]

Astromon: way cooL thanks guys [12:14 AM]

rhiju: it took a while to both do the experiments and to analyze the many different kinds of puzzles that you helped us pilot [12:14 AM]

Astromon: the rest of round 98? [12:14 AM]

jnicol: coophttp://www.eternagame.org/web/lab/6089812/ [12:14 AM]

Astromon: er 99 maybe? [12:14 AM]

Tigerlrg245: Ahh, i see. [12:14 AM]

jnicol: R98 [12:15 AM]

rhiju: @jnicol, is it possible to get the dsign leaderboard to show up for the coop results? [12:15 AM]

Astromon: Yay [12:15 AM]

jnicol: yes, working on it [12:15 AM]

Astromon: i knew there were many more untested designs left in 98<< [12:16 AM]

Astromon: prob some more too [12:16 AM]

rhiju: johan's spreadsheet is here --https://docs.google.com/spreadsheets/d/1VdCX8zYoRdgHQEwxgaGCbPfvsb4seZFWstcVECh3mCQ/edit [12:17 AM]

rhiju: still needs to get uploaded into the game [12:17 AM]

Astromon: There is no designer name in the spreadsheet again? [12:17 AM]

Elves: cool! [12:18 AM]

johana: @Astromon: Yes, there were many different experiments, some of which were performed and analyzed separately, so there will be more [12:18 AM]

Astromon: yup   how about us descussing last dev meeting to put the designers name and eterna score in the spread sheet back to back [12:19 AM]

Jennifer Pearl: cim back computer crashed [12:19 AM]

Tigerlrg245: Welcome back  [12:19 AM]

johana: For the cooperativity puzzles, this round worked really well thanks to a lot of data points for each design. Some scored higher than 90, with Hill coefficients almost reaching 2. [12:19 AM]

Astromon: was that not posible to do this time or something? [12:20 AM]

Jennifer Pearl: what did i miss [12:20 AM]

johana: We think that it is very exciting because it shows that these types of puzzles work and that players are able to design some really interesting things [12:20 AM]

rhiju: you all made switches with sharp responses [12:21 AM]

Astromon: sharp on off [12:21 AM]

Tigerlrg245: Awesome. So now you're running it again to get more results? [12:21 AM]

rhiju: we weren't sure if that was possible to design rationally or to measure with our experiments -- turns out we can now do both. very cool. [12:22 AM]

Jennifer Pearl: that is cool [12:22 AM]

rhiju: yes, let's see if we can get more designs with sharp responses  [12:22 AM]

Jennifer Pearl: so it is confirmed that we can do measurments and such with RNA? [12:22 AM]

rhiju: and can we learn rules that would let us design cooperative binders for other molecules [12:22 AM]

johana: @Astromon: Putting the player names in the spreadsheet is a good idea for the future. The R98 data were generated  (but perhaps not published) before last dev chat [12:22 AM]

Astromon: well let me look for my test results it shouls only take about two hours since it was decided Again not to put the designers name in the spreadsheet [12:23 AM]

Astromon: so be it [12:23 AM]

rhiju: @astromon or you can bug jnicol to get the results uploaded into the game's solution browser!  [12:24 AM]

rhiju: in the near future, we'll be deploying a better in-game data browser too. [12:24 AM]

Jennifer Pearl: cool [12:24 AM]

Astromon: so do we expect more 98 results back before any of 99 ? [12:24 AM]

Astromon: cooL thanks riju [12:25 AM]

johana: Yes, all R98 scores will come before R99. [12:25 AM]

jandersonlee: Will the XOR lab ever be rerun? [12:25 AM]

Astromon: the browser takes along time to get results too [12:25 AM]

Astromon: its best with designer name in spreadsheet MeechI actually did it for round 97 it was very good work [12:26 AM]

jandersonlee: or are we doing TBA/TBB instead [12:26 AM]

Astromon: what line is the eterna score on this time? [12:27 AM]

johana: @jandersonlee: I hope so. The XOR puzzles actually worked quite well, with many successful designs, and it would be great to see if we can improve further. [12:27 AM]

rhiju: @jandersonlee, we won't be able to make a final decision on when puzzles will be re-run until we get the data back for the first round of A/B. [12:28 AM]

Elves: better in game data browser will be awesome [12:28 AM]

Jennifer Pearl: i agree [12:28 AM]

rhiju: So far, though, all the different puzzles that we've tried in the lab have led to success.  [12:28 AM]

jandersonlee: still "cooking" the data? [12:28 AM]

rhiju: at this time last year, it was not even clear if we could set up puzzles for A/B or XOR or coperativity or even the now-classic FMN/MS2 switches. [12:29 AM]

Astromon: my scores so far are very low [12:29 AM]

Jennifer Pearl: wow we ahve made alot of progress!! [12:29 AM]

Elves: it's really good news that we got back confirmation that we can design intelligently, great work everyone who made designs! [12:29 AM]

rhiju: its really amazing to me that (1) our dev team has figured out how to set up the puzzles, (2) you the community have produced solutions that work, and (3) johan can actually experiementally verify this [12:29 AM]

jandersonlee: can I put in a plug for the switch version of StrategyMarket? We need analysis of lab results [12:30 AM]

johana: @jandersonlee: Yes. data and plots are "cooking" [12:29 AM]

Elves: thanks janderson that is a good idea [12:30 AM]

Astromon: thats great! [12:30 AM]

rhiju: @jandersonlee, very briefly, we did compile player strategies frmo a strategy market expt this summer [12:30 AM]

Omei: @johana, have you posted something on the meaning of the  cooperativity spreadsheet columns?  There seem to be more than I can interpret, or remember from the first round. [12:30 AM]

rhiju: that effort was led by vineetkosaraju and new designs were automatically generated and submitted by a revamped eternabot [12:30 AM]

rhiju: unfortunately they didn't fare much better than the solutions without the extra strategies [12:31 AM]

Astromon: funny my designs name for this lab is lettheforcebewyou haha [12:31 AM]

johana: @omei: Good idea. The scores are explained, but I can try to put together an explanation of each columnn in the data dset [12:31 AM]

Jennifer Pearl: i rememebr this I think [12:31 AM]

Astromon: and the results come out today!  :D [12:31 AM]

jandersonlee: @rhiju never hear any feedback to the Citizen Scinetists on what strategies worked [12:31 AM]

rhiju: but that effort led to lots of back-and-forht with players, and we realized that it might be better to focus on strategies that define where to put the aptamers and protein binidng sites relative to each other  [12:31 AM]

Omei: @johana: Thanks. [12:32 AM]

jandersonlee: @rhiuju - yes I think geometry may play a big role in switches [12:32 AM]

rhiju: see, e.g., eli's summary of that: https://getsatisfaction.com/eternagame/topics/blueprint-of-the-ms2-and-fmn-riboswitch [12:32 AM]

rhiju: and those discussions have led to the current lab puzzles, which eli & omei actually put together to test specific hypotheses about 'blueprint' of structures (rather than sequence features) [12:33 AM]

Astromon: please tell me letter I isnt the eterna score [12:33 AM]

rhiju: so please do submit a lot of solutions to the current lab -- it may be the final step in a very important investigation on how to make 'perfect' riboswitches [12:33 AM]

Jennifer Pearl: depending on where teh binding site is the designs do tend to have a bit different profile for some of the values that RNAfold kicks out [12:33 AM]

Astromon: oh thank god it J! [12:34 AM]

Astromon: i was seeing my scores as 12 and 15 lol [12:35 AM]

jandersonlee: isn't it hard to avoid apples/oranges comparisons with different geometries? [12:35 AM]

rhiju: @jennifer, yes exactly ...  [12:35 AM]

Jennifer Pearl: i noticed that for all the NG round 1 labs [12:35 AM]

rhiju: @astromon, yes the column is J. :) [12:35 AM]

Astromon: YAY [12:35 AM]


Tigerlrg245: @rhiju i recently checked the lab description again and i realized i didn't really focus on any hypothesis, and i actually not really understand what does that mean, do you have an example of a possible hypothesis to solve by? [12:35 AM]

Astromon: sry caps [12:35 AM]

Astromon: ill wait [12:36 AM]

Jennifer Pearl: i feel like there may be  a configuration that is "easier" to design for but not alot of proof yet just a hunch [12:36 AM]

rhiju: @tigerlrg245, I think jennifer pearl, astromon, and others here have really good examples of hypotheses that they are testing ... and in some cases are helping them achive consistent success [12:36 AM]

Tigerlrg245: @rhiju allright, ill ask around [12:37 AM]

Astromon: its only 1 time a week we get to have it [12:37 AM]

rhiju: oh wait, jandersonlee is here too -- let me point you to his work on A/B, where he simulated all the community designs -- he then has logged predictions as to which designs will work best. There, the hypothesis is that the NUPACK simulation package gives an acccurate representation of the RNA behavior, enough to design great RNA caluclators'. [12:38 AM]

rhiju: @tigerlrg245 -- check the comments section here: http://www.eternagame.org/web/lab/6204762/ [12:38 AM]

Astromon: way cooL [12:38 AM]

Jennifer Pearl: nice [12:38 AM]

jandersonlee: which we won't know untill we get A/B results back [12:38 AM]

Tigerlrg245: thanks! i was actually just going to ask him about hypothesis because he looked to me like he'd know that [12:38 AM]

rhiju: also, jen pearl is submitting designs based on a set of methods and ideas called DPAT & remmy [12:39 AM]

Astromon: awesome janderson! [12:39 AM]

Astromon: YaY jen thanks jen! [12:39 AM]

Tigerlrg245: Well, is there any options for people less smart haha [12:39 AM]

rhiju: those are pretty sophisticated -- players using separate software tools. But more generic hypotheses are useful (sometimes more useful) -- eli has a good summary of hypotheses in his post: https://getsatisfaction.com/eternagame/topics/blueprint-of-the-ms2-and-fmn-riboswitch [12:39 AM]

Astromon: i thought the a/b labs were very fun [12:39 AM]

rhiju: @astromon great to hear! if the data look good, we'll have some exciting puzzles in 2016 where A andB (and another gene C) will be the RNAs that actually report on active tuberculosis infection [12:40 AM]

Tigerlrg245: wait - are hypothesists what you make a new labs about or do you need one for designs you submit? [12:40 AM]

jandersonlee: OK, so #NuPACK might mean a deisgn that NuPACK favors then? [12:40 AM]

rhiju: we'll actually want to calculate A*B/C*C -- nando alerady has set up a test puzzle (but not yet deployed to players) [12:41 AM]

rhiju: @jandersonlee yes that sounds nice  [12:41 AM]

Jennifer Pearl: im testing out a theory that transitional states that we observed awhile ago are predicted by Vienna 2 and that some structures are indicators of good designs [12:41 AM]

rhiju: actually, can you put that in the forum thread on this? the one that omei started [12:41 AM]

Elves: @tiger a hypothesis could be anything, like 'I used 70% GC bonds' which may work in solid state puzzles but not in switches [12:41 AM]

jandersonlee: hmm - OK will rethink my submission strategy [12:41 AM]

rhiju: hashtags: https://getsatisfaction.com/eternagame/topics/using-hashtags-to-improve-lab-collaboration-and-experimentation [12:41 AM]

johana: Hypotheses could be that the presence of secondary structures and/or sequences improve the switching. In the submissions, you can test these by making various designs [12:41 AM]

Nando: @tiger: an example hypothesis, which I think I never heard talk about in the channel: is the FMN binding bonus constant, or does it depend on factors like neighboring base pairs around the loop? [12:41 AM]

Elves: nice one Nando! [12:42 AM]

Nando: (and their orientation) [12:42 AM]

Nando: hi everyone [12:42 AM]

jandersonlee: Hi Nando [12:42 AM]

Tigerlrg245: hey nando, thanks for the example [12:42 AM]

Jennifer Pearl: hi nando [12:42 AM]

Astromon: i have a feeling this dev meeting will be a good one to review later [12:43 AM]

Astromon: hi Nando welcome [12:43 AM]

jandersonlee: Is there some way to make the StrategyMarket framework available through the EternaScript interface? [12:43 AM]

johana: ji Nando, that's a good hypothesis [12:43 AM]

rhiju: @tiger or a hypothesis could be simpler, like its best to use GU pairs in the stems that switch. After that, you should look at designs (or submit them) that the hypothesis predicts will be better or worse, e.g., with more or less GU pairs. And when the data comes out you'll find out if the hypothesis was right or not. Tell us what you found on the wiki, forum, and these chats --And that's how science mo [12:43 AM]

Elves: @rhiju cut off at 'and that's how science mo... [12:44 AM]

rhiju: @jandersonlee, that's a great idea, but we ended up coding strategies in python -- if interested we can give you read access to the repo -- send me a PM. [12:44 AM]

rhiju: @Elves and that's how science moves forward! [12:44 AM]

jandersonlee: @rhiju with an StrategyMarket framework we could test the hypothesis that GUs help on existing lab results [12:44 AM]

Tigerlrg245: Oh i think i get it now, thanks [12:44 AM]

Jennifer Pearl: i like python [12:44 AM]

Jennifer Pearl: that is what i took in school [12:44 AM]

Astromon: my hypotheses states that i will go back to a certain piont after making (passing) constraints and doing it a bit  diferent to get a nice variety of designs [12:45 AM]

jandersonlee: @rhihu - I can handle python - will PM [12:45 AM]

Elves: :D [12:45 AM]

Tigerlrg245: so the hypothesis is made with the lab opened and the idea is to get results that will help test that one, thanks for so many answers :) [12:45 AM]

johana: Yes. The labs are designed partly to allow players to test some promising hypotheses. [12:45 AM]

Astromon: i hope i did it right<< [12:46 AM]

Elves: yeah the main point of a hypothesis is to take an educated guess, or even a wild guess, that you codify into a single strategy, no matter how simple or complex. then we test whether it works by getting real... [12:46 AM]

...life lab results back

johana: The latest round, as you noticed, has more puzzles than usual to allow for more rigorous testing, notably in how the different modules are arranged [12:46 AM]

jandersonlee: s a stratgey might be that %GUs un switching area is significant on ablity to switch [12:46 AM]

rhiju: @jandersonlee yes the strategy market framework allows for automation of hypothesis testing, but it is bottlenecked by the ability and speed of a dev to code up strategies. I do think though that a lot of the new things eterna has discovered does not require automation but just creative players making predictions for which designs will work. The hashtags should help organize that.  [12:47 AM]

Jennifer Pearl: @rhiju [12:47 AM]

whbob: Hi.  [12:47 AM]

Tigerlrg245: Allright, guess i should be using hash tags from now on [12:47 AM]

jandersonlee: @rhiju - unbottleneck with open source - allow programmer players to code their own strategies [12:48 AM]

rhiju: like there could be a #GUinswitchstem. BTW, I think that's an idea from one of Eli's docs, and it may have come from a diferent player (maybe even you @jandersonlee) -- sorry I don't remember who. [12:48 AM]

Tigerlrg245: @jandersonlee wait so are you the one working on mathematical calculations with rna? that's awesome! how does it work? [12:48 AM]

Jennifer Pearl: @rhiju I was thinking about using DPAT to make predicitons of what designs that were submitted were doing well. How would I do that? Can I add hashtags to someones design comments? [12:48 AM]

Elves: the basic idea with hashtags is to put #strategyName in your lab design description so we can easily tell which designs go with that strategy, is that correct rhiju? [12:48 AM]

Elves: Jen that's an interesting idea [12:49 AM]

rhiju: @jandersonlee yup that was the original idea. but even open source needs someone to set the organization and monitor commits. now if you're interested in being that person...  [12:49 AM]

Elves: :D [12:49 AM]

jandersonlee: @Tiger use OpenSource NuPACK code plus python to check predictions of folding/switching based on base paring estimates [12:49 AM]

Astromon: oH its a description of ones design stratigy!! [12:49 AM]

rhiju: @elves yes, that's the basic idea -- nando & omei might be able to elaborate. our new design browser will allow for easy filtering by hashtag. [12:49 AM]

Astromon: hmm i can do this [12:49 AM]

Elves: oooo nice [12:50 AM]

jandersonlee: @rhiju - I wish - limited time these days [12:50 AM]

Astromon: i jst got some good ideas about this! [12:50 AM]

Jennifer Pearl: I'll make a getsat about adding hashtags to another players design [12:50 AM]

rhiju: actually the current design browser can filter/search by hashtag too in the description. we just need to start a cultuer of using hashtags in the community. [12:50 AM]

rhiju: @jennifer cool thanks! also remember that omei has initiated a nice thread on this: https://getsatisfaction.com/eternagame/topics/using-hashtags-to-improve-lab-collaboration-and-experimentation [12:50 AM]

jandersonlee: #hashtags in comments would allow other players to annotate [12:50 AM]

Jennifer Pearl: i think it would be  agood idea [12:51 AM]

rhiju: @jandersonlee oh that's a great point. [12:51 AM]

Brourd: Perhaps it would be a good idea for select players to generate a list of viable hypotheses that new or lost players could use if they wish to do so, as well as listing all hypotheses being tested so far. [11:51 AM]

rhiju: @omei are we including search of comment in the new browser? [12:51 AM]

Jennifer Pearl: im posting a comment nowish [12:51 AM]

Elves: @Brourd that's an awesome idea!! [12:51 AM]

jandersonlee: @Brourd +1 [12:52 AM]

Elves: since we want clusters / batches of unique designs for each hypothesis, that would be a huge help to the hypothesis  [12:52 AM]

Omei: Well, comments hadn't occurred to me as something to unclude in the browser.  [12:52 AM]

rhiju: @brourd, one option would be to link each project to a wiki, where the community could collate thoughts, including various hashtags. some of the gory detail in our lab text descriptions could go there too. [12:52 AM]

Brourd: Indeed. [11:53 AM]

rhiju: @omei @jandersonlee that's why we have dev chats. :)  [12:53 AM]

Elves: hashtag library  [12:53 AM]

Elves: also functioning as strategy library [12:53 AM]

Astromon: good idea riju [12:53 AM]

johana: @Brourd: Nice, to get into that way of thinking. Eli's document does this in a way, so distilling it into an itemized list could be usful [12:53 AM]

rhiju: @omei @nando actually we previously discussed having author-editable descriptions (currently they are not editable). maybe we don't have to do that if we allow search in comments (and authors can of course add comments). [12:53 AM]

Astromon:  I would like to  see a link on this page that takes you to the winning lab designs last 10 rounds with pics of them maybe even videos explaining the logic behind those designs  and patterns we could use for future designs   [12:53 AM]

jandersonlee: a forum post could be a way to allow users to add new ideas/hashtags [12:54 AM]

Brourd: More than an itemized list though, Johan. Using Rhiju's idea of wiki pages, it would allow for detailed summaries of the hypotheses as well. [11:54 AM]

Elves: thanks Johan, do you have a link or title by any chance? or is it a forum post from earlier in chat? [12:54 AM]

johana: @elves: Yes, it's a forum post. See above. [12:54 AM]

Omei: I think the ability to edit titles and descriptions is still important, even beyond hashtags. [12:55 AM]

rhiju: @everyone we have to go soon -- wanted to ask: does this time 12pm PST work better/worse than 3pm PST for most folks? or for others you know who weren't able to make it? [12:55 AM]

Elves: ok thanks! i thought i saw it go by :D [12:55 AM]

Jennifer Pearl: just posted about the hashtags in comments [12:55 AM]

rhiju: @omei good point on titles. [12:55 AM]

jandersonlee: luch time works for me [12:55 AM]

jandersonlee: s/luch/lunch/ [12:55 AM]

Astromon: its a fine time for me riju<< [12:55 AM]

Jennifer Pearl: works for me [12:55 AM]

Elves: this is a good time for me [12:55 AM]

Nando: works well for me too [12:56 AM]

whbob: Time is OK for me, even though I was late today:( [12:56 AM]

Jennifer Pearl: hi whbob [12:56 AM]

Tigerlrg245: If it helps it works for me, but i'm just here to ask questions I'm not very good at science and stuff haha [12:56 AM]

rhiju: hi whbob! [12:56 AM]

Elves: hi whbob! new dev chat time :) [12:56 AM]

whbob: HI all! [12:56 AM]

Tigerlrg245: hello :) [12:56 AM]

Astromon: hi bob [12:56 AM]

rhiju: @tiger you're going to be good in no time -- welcome to a great community [12:56 AM]

Elves: you're doing great tiger! one step at a time [12:56 AM]

Brourd: Unfortunately, it coincides with a physics lab next semester. But I'm too busy to make these chats most of the time anyway. [11:57 AM]

Tigerlrg245: @rhiju it does seem like a fantastic community from the short time that i was here :] [12:57 AM]

Elves: congrats on all your school progress Brourd, big high five :) :) :) [12:57 AM]

Nando: the joys of QFT, aaahhh.... I envy you, B [12:57 AM]

jandersonlee: yes. congrats [12:57 AM]

Jennifer Pearl: wanted to breing up the idea of Eternacon next year? [12:58 AM]

Jennifer Pearl: been meeing to bring up the though [12:58 AM]

Jennifer Pearl: thoguht [12:58 AM]

Jennifer Pearl: thought [12:58 AM]

rhiju: @jen wow, good point. we don't have an organizer yet [12:58 AM]

Jennifer Pearl: i would love to help out [12:58 AM]

jandersonlee: you volunteering Jen? ;) [12:58 AM]

Jennifer Pearl: i want it to happen [12:58 AM]

Jennifer Pearl: ummmm i think i might be [12:58 AM]

rhiju: maybe a couple folks + one stanford person [12:59 AM]

rhiju: that worked really well last year (tomoe+lroppy+vineet+pablo) [12:59 AM]

Jennifer Pearl: I can get the ball rolling abd talk with some of the orginizers of last years event and see where we need to start but I have some ideas [12:59 AM]

Jennifer Pearl: main think is location, and travel, and money [12:59 AM]

jandersonlee: I can handle Stanford/Palo Alto [1:00 PM]

Jennifer Pearl: i liked standford. I went this year and it was great [1:00 PM]

jandersonlee: and it makes it easier for more lab folks to show up [1:00 PM]

rhiju: we'll have a better idea on budget in late january/early february -- eterna is waiting to hear on a grant  submitted to the NSF. for a very cool new direction in 2016-2017. cross your fingers. [1:00 PM]

jandersonlee: X [1:01 PM]

Jennifer Pearl: X [1:01 PM]

rhiju: what do you all think of sponsors? [1:01 PM]

rhiju: probably around $20k for the whole event, incl. travel help to some players [1:01 PM]

Elves: toes, fingers and elbow crossed :D [1:01 PM]

rhiju: more money would also let us bring in players from overseas. [1:01 PM]

Jennifer Pearl: if it helps get teh job dont then cool but not if they impose restrictions [1:01 PM]

Astromon: +0 [1:01 PM]

Brourd: I suppose if we only have to drink Pepsi and Pepsico products, it would be for the best. [12:02 AM]

Jennifer Pearl: sponsers for Eternacon would be great though [1:02 PM]

Jennifer Pearl: i ws thinking for eterna in general at first [1:02 PM]

rhiju: sponsors might include novartis (pharma company) or local synthetic biology companies like transcriptic or agilent. [1:02 PM]

jandersonlee: sponsors for the 'Con OK - the web site, not so much [1:02 PM]

rhiju: they'd probably have a booth at the con. [1:02 PM]

Jennifer Pearl: I would like to see people from overseas come,. [1:03 PM]

rhiju: depending on how much they paid, they could also get 10 mins to talk in the main program. [1:03 PM]

jandersonlee: Job Recruiting? [1:03 PM]

Jennifer Pearl: @rhiju i think it would be a good idea to start speaking with possible sponsors [1:03 PM]

rhiju: @jandersonlee, right, no sponsors on site.  [1:03 PM]

Elves: i'd like to pre-vet their content  [1:03 PM]

rhiju: @jennifer pearl, pretty soon! we're going to have some press in the new year in january/february, so might be best to time it near then. [1:04 PM]

rhiju: the press will be for the eterna-mdeicine release ,and also for the first player-led paper from eterna -- actually from any citizen science project. some of you here in the chat (you know who you are) are lead authors. [1:04 PM]

Jennifer Pearl: we could have a committee to review sponsors and what the deals are [1:04 PM]

jandersonlee: @rhiju - the paper? [1:04 PM]

rhiju: that's going to be exciting. [1:04 PM]

Elves: like ask them to submit whatever the booth promotes and whatever statements they will make, so that we know what we are associating with [1:04 PM]

rhiju: @jandersonlee yup, that paper. [1:05 PM]

rhiju: i've got to go guys -- see you in 2 weeks at the next dev chat! have a great holiday! [1:05 PM]

Nando: bye rhiju [1:05 PM]

johana: Same. See you next time! [1:05 PM]

Jennifer Pearl: @rhiju that would be cool i just worry about wheher we ilklhave time to make money by July [1:05 PM]

Elves: thanks for sharing all the great news! [1:05 PM]

jandersonlee: Happy Holidays Everyone [1:05 PM]

Jennifer Pearl: see you  [1:05 PM]

Elves: happy holidays :) :) :) [1:06 PM]

Tigerlrg245: off topic suggestion, but did anyone think of making an option to change nueclotides without recalculating the shape? just so you can make a few changes without waiting for it all to calculate every single change (it can lag on large puzzles) [1:06 PM]

whbob: Bye Rhiju:) [1:06 PM]

Jennifer Pearl: I will start a getsat for this and talk with people [1:06 PM]

Tigerlrg245: happy hanuka everyone [1:06 PM]

Elves: tiger like a manual shape calc mode? [1:06 PM]

Astromon: u2 tig [1:06 PM]

Elves: that's interesting, you could make a forum post suggesting it [1:07 PM]

Astromon: thsnks all nice chat [1:06 PM]

Elves: thanks everyone! have a great weekend [1:07 PM]

Tigerlrg245: Allright, I'll make something like that [1:07 PM]

Tigerlrg245: you too Elves! :) [1:07 PM]

Astromon: I would like to  see a link on this page that takes you to the winning lab designs last 10 rounds with pics of them maybe even videos explaining the logic behind those designs  and patterns we could use for future designs   [1:07 PM]

Elves: thx :) [1:07 PM]

Astromon: sry i didnt know if anyone saw that^ [1:07 PM]

Jennifer Pearl: not sure how that woudl be implementd Astro [1:07 PM]

Elves: astro that's cool, forum post it!! [1:07 PM]

Jennifer Pearl: I would bring that up in a GetSat [1:07 PM]

Astromon: just a link on the main page [1:08 PM]

Elves: everything takes dev time so it's a matter of getting ideas in the queue and as bandwidth is available we crunch through the suggestions [1:08 PM]

Astromon: oKay! [1:08 PM]