The ribosome is the nanomachine that translates RNA bases from messenger RNA into amino acids and proteins. The principle function of a ribosome is to take messenger RNA (mRNA) derived from genes (typically stored as DNA) and use them as a template or recipe to construct poly-peptides (proteins) by matching 3-base RNA triplets (codons), one at a time, to amino acids using transfer RNA (tRNA) to aid in the process.
Teaching about Ribosomes
Labs and Puzzles for Ribosomes
- Ribosome Pilot Challenge Warm-Up Lab
- Ribosome Pilot Challenge Lab
- Ribosome Challenge Puzzles
- Ribosome Player-Puzzles
Selected Forum Posts
- Redesigning the ribosome: chemical goals
- Ribosome Challenge Puzzles of the Week
- Domain structure of the Ribosome
- Pilot Challenge
Puzzle Solving Resources
- prestonzen is creating another great resource for learning to solve Eterna puzzles -- YouTube video walk-throughs. His first Ribosome Challenge video, where he solves puzzle 1.7, is a very gentle introduction.
- Astromon's Guide for the Ribosome labs/challenges and The Soft Constraint booster.
- Eli's Solving ribosome challenge puzzles document.
Puzzle Construction/Analysis Resources
- Ribosome Challenge Puzzle Creation contains the scondary structure, starting sequence, IUPAC constraints and locks for the three major robosome units and their domains.
- Secondary structure diagrams for E. coli and related bacteria