Melt Plot

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A melt plot shows how many bases are unpaired at different temperatures for a particular RNA sequence; note that different RNA sequences will have different melt plots. At high enough temperatures, all RNA sequences will have 100% of their bases unpaired. But at lower temperatures, only some of the bases will be unpaired - these unpaired bases belong to loops, bulges, and dangling ends.

The melt plot describes how an RNA unfolds as temperature increases.

Teaching about melt plots

See also